Journal: Small (Weinheim an Der Bergstrasse, Germany)

Article Title: Rapid Structural Analysis of Natural Products Using MicroED

doi: 10.1002/smll.202511875

Figure Lengend Snippet: (A) Chemical structure of 1 ; (B) MicroED structure of 1 , 2F o ‐F c density map was shown in a blue mesh at 3σ contour level; (C) Representative diffraction pattern (658 mm) and crystal appearance (SA 5300x) of 1 under TEM. Scale bar: 2 µm; (D) Packing diagram in 1 , viewed along b ‐ or c ‐ axis. Hydrogen bonding interactions were presented in orange dashed lines.

Article Snippet: The parallel beam (∼45.2% intensity) was tuned using a 500 nm diffraction grating replica (prod.# 673; Ted Pella, Inc.) and 70 μm objective aperture at the back focal plane.

Techniques:

Journal: Small (Weinheim an Der Bergstrasse, Germany)

Article Title: Rapid Structural Analysis of Natural Products Using MicroED

doi: 10.1002/smll.202511875

Figure Lengend Snippet: (A) Chemical structure of 9 ; (B) MicroED structure of 9 , 2F o ‐F c density map was shown in a blue mesh at 3σ contour level; (C) Representative diffraction pattern (658 mm) and crystal appearance (SA 5300x) of 9 under TEM. Scale bar: 2 µm; (D) Weak C─H···O hydrogen bonding interaction for one molecule of 9 . (E) Packing diagram in 9 , viewed along the a ‐axis. Hydrogen bonding interactions were presented in blue dashed lines.

Article Snippet: The parallel beam (∼45.2% intensity) was tuned using a 500 nm diffraction grating replica (prod.# 673; Ted Pella, Inc.) and 70 μm objective aperture at the back focal plane.

Techniques:

Journal: Small (Weinheim an Der Bergstrasse, Germany)

Article Title: Rapid Structural Analysis of Natural Products Using MicroED

doi: 10.1002/smll.202511875

Figure Lengend Snippet: (A) Chemical structure of 2 ; (B) MicroED structure of 2 , 2F o ‐F c density map was shown in a blue mesh at 3σ contour level; (C) Representative diffraction pattern (658 mm) and crystal appearance (SA 5300x) of 2 under TEM. Scale bar: 2 µm; (D) Polymorphic structures and packing diagram in 2 , viewed along b ‐axis. Hydrogen bonding interactions were presented in orange dashed lines. Hydrogen atoms not involved in contact were omitted for clarification.

Article Snippet: The parallel beam (∼45.2% intensity) was tuned using a 500 nm diffraction grating replica (prod.# 673; Ted Pella, Inc.) and 70 μm objective aperture at the back focal plane.

Techniques: Clarification Assay

Journal: Small (Weinheim an Der Bergstrasse, Germany)

Article Title: Rapid Structural Analysis of Natural Products Using MicroED

doi: 10.1002/smll.202511875

Figure Lengend Snippet: (A) Chemical structure of 4 ; (B) MicroED structure of 4 , 2F o ‐F c density map was shown in a blue mesh at 3σ contour level; (C) Representative diffraction pattern (658 mm) and crystal appearance (SA 5300x) of 4 under TEM. Scale bar: 2 µm; (D) Packing diagram in 4 , viewed along the a ‐axis. Hydrogen bonding interactions were presented in orange dashed lines.

Article Snippet: The parallel beam (∼45.2% intensity) was tuned using a 500 nm diffraction grating replica (prod.# 673; Ted Pella, Inc.) and 70 μm objective aperture at the back focal plane.

Techniques:

Journal: Small (Weinheim an Der Bergstrasse, Germany)

Article Title: Rapid Structural Analysis of Natural Products Using MicroED

doi: 10.1002/smll.202511875

Figure Lengend Snippet: (A) Chemical structure of 5 ; (B) MicroED structure of 5 , 2F o ‐F c density map was shown in a blue mesh at 3σ contour level; (C) Representative diffraction pattern (658 mm) and crystal appearance (SA 5300x) of 5 under TEM. Scale bar: 2 µm; (D) Packing diagram in 5 , viewed along the a ‐axis. π‐π and hydrogen bonding interactions were presented in orange dashed lines.

Article Snippet: The parallel beam (∼45.2% intensity) was tuned using a 500 nm diffraction grating replica (prod.# 673; Ted Pella, Inc.) and 70 μm objective aperture at the back focal plane.

Techniques:

Journal: Small (Weinheim an Der Bergstrasse, Germany)

Article Title: Rapid Structural Analysis of Natural Products Using MicroED

doi: 10.1002/smll.202511875

Figure Lengend Snippet: (A) Chemical structure of 6 ; (B) MicroED structure of 6 , 2F o ‐F c density map was shown in a blue mesh at 3σ contour level; (C) Representative diffraction pattern (658 mm) and crystal appearance (SA 5300x) of 6 under TEM. Scale bar: 2 µm; (D) Packing diagram in 6 , viewed along a ‐ or b ‐axis. Hydrogen bonding interactions were presented in orange dashed lines. π‐π interactions were presented in green dashed lines. Hydrogen atoms not involved in contact were omitted for clarification.

Article Snippet: The parallel beam (∼45.2% intensity) was tuned using a 500 nm diffraction grating replica (prod.# 673; Ted Pella, Inc.) and 70 μm objective aperture at the back focal plane.

Techniques: Clarification Assay

Journal: Small (Weinheim an Der Bergstrasse, Germany)

Article Title: Rapid Structural Analysis of Natural Products Using MicroED

doi: 10.1002/smll.202511875

Figure Lengend Snippet: (A) Chemical structure of 7 ; (B) MicroED structure of 7 , 2F o ‐F c density map was shown in a blue mesh at 3σ contour level; (C) Representative diffraction pattern (658 mm) and crystal appearance (SA 5300x) of 7 under TEM. Scale bar: 2 µm; (D) Packing diagram in 7 , viewed along the a ‐axis. Forms 1 and 2 were presented in purple and yellow, respectively. Hydrogen bonding interactions were presented in blue dashed lines.

Article Snippet: The parallel beam (∼45.2% intensity) was tuned using a 500 nm diffraction grating replica (prod.# 673; Ted Pella, Inc.) and 70 μm objective aperture at the back focal plane.

Techniques:

Journal: Small (Weinheim an Der Bergstrasse, Germany)

Article Title: Rapid Structural Analysis of Natural Products Using MicroED

doi: 10.1002/smll.202511875

Figure Lengend Snippet: (A) Chemical structure of 8 ; (B) MicroED structure of 8 , 2F o ‐F c density map was shown in a blue mesh at 3σ contour level; (C) Representative diffraction pattern (658 mm) and crystal appearance (SA 5300x) of 8 under TEM. Scale bar: 2 µm; (D) Packing diagram in 8 , viewed along the a ‐axis. Hydrogen bonding interactions were presented in blue and green dashed lines. Water molecules were colored in purple balls.

Article Snippet: The parallel beam (∼45.2% intensity) was tuned using a 500 nm diffraction grating replica (prod.# 673; Ted Pella, Inc.) and 70 μm objective aperture at the back focal plane.

Techniques:

Journal: Small (Weinheim an Der Bergstrasse, Germany)

Article Title: Rapid Structural Analysis of Natural Products Using MicroED

doi: 10.1002/smll.202511875

Figure Lengend Snippet: (A) Chemical structure of 3 ; (B) MicroED structure of 3 , 2F o ‐F c density map was shown in a blue mesh at 3σ contour level; (C) Representative diffraction pattern (658 mm) and crystal appearance (SA 5300x) of 3 under TEM. Scale bar: 2 µm; (D) Packing diagram in 3 , viewed along the a ‐axis. Hydrogen bonding interactions were presented in orange and cyan dashed lines. Molecules were colored by their symmetries.

Article Snippet: The parallel beam (∼45.2% intensity) was tuned using a 500 nm diffraction grating replica (prod.# 673; Ted Pella, Inc.) and 70 μm objective aperture at the back focal plane.

Techniques: